BIOL 1090 Lecture Notes - Lecture 19: Nuclear Pore, Nuclear Lamina, Sister Chromatids
6 Jul 2015
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Dynamic network of filaments and tubules that extend through the cytosol. Intracellular transport: contractility and motility, spatial organization within cell. 2 types: axonemal, organized and stable, cytoplasmic, dynamic, located in cytosol. Stabilize mts or stimulate assembly. Exclusive to multicellular animals. Provide structural support and mechanical strength. Kinesin (plus end directed) and dynein (minus end directed) Polymer of protein actin. Several functions: maintenance of cell shape, cell movement, cytokinesis, muscle contraction. F- actin microfilament: polar structure, highly branched networks, assembly, g- actin polymerizes reversibly, nucleation (slow): G- actin dimers trimers short filaments: elongation (fast): Monomers add to both ends. Unconventional (all other types: generate force and contribute to mobility in non- muscle cells. The coordinate activity of actin- binding proteins controls microfilament formation in a lamellipodium to allow directed movement of cells. Lecture 11: storage, replication, and repair of genetic material, transcription (mrna, trna, rrna) and splicing. Envelope: 2 parallel phospholipid bilayers, outer membrane binds ribosomes and is continuous with rer.
