BIOL 1090 Lecture Notes - Lecture 9: Cytosol, John Wiley & Sons, Secretion

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P r e v i o u s l y i n l e c t u r e 8 . http://publications. nigms. nih. gov/insidethecell/extras/golgi/itc_vesicularshuttle. html. 4: alanine (a), valine (v) and proline (p) are hydrophobic amino acids whereas arginine (r) and lysine (k) are charged amino acids. (m = methionine) Which of the following is most likely a signal sequence: m-k-k-v-r-k-r-m, v-v-a-p-a-v-p-p, m-v-p-p-a-v-a-p, k-k-r-k-m-m-k-k. Function cytosol nucleus protein synthesis, many metabolic pathways contains genome, dna, rna synthesis, ribosome assembly endoplasmic reticulum (er) synthesis of lipids, synthesis of proteins. Golgi apparatus lysosomes endosomes mitochondria chloroplasts peroxisomes protein modification, packaging of proteins and lipids degradation of cellular material sorting, recycling. Atp synthesis, apoptosis photosynthesis, atp synthesis oxidation of toxic molecules. Clathrin-coated vesicles move from tgn to other vesicles (e. g. lysosomes, endosomes, plant vacuoles) = exocytosis: constitutive, regulated (e. g. neurotransmitter secretion) Lysosomes digestive organelles: 25 nm - 1000 nm, internal ph of 4. 6, h+-atpase, hydrolytic enzymes. Glycosylated proteins: protective lining next to lumen.

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