BIOL 1090 Lecture 8: 8. Transcription and RNA processing

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Transcription and translation occur at the same time; coupled. Rna transcripts are transported to the cytoplasm fir translation mrnas. Intermediates that carry genetic information from dna to the ribosomes. Adaptors between amino acids and the codons in mrna rrnas. Structural and catalytic components of ribosomes snrna and snorna. Short single-stranded rnas that block expression of complementary mrna. Only one strand of dna is used as a template. Rna chains can be initiated with no primer required. Rna molecules will be complementary to the dna template strand and identical to the dna non-template strand. Rna synthesis is catalyzed by rna polymerases and proceeds in the 5->3 direction. Initiates about 5-9 base pairs down from the end of the -10 sequence. 5" end of the rna is usually a purine. Rna polymerase has helix unwinding and rewinding activities. Weak h-bonding at u:a residues allows mrna release from dna when. Rna/protein structure snrnaa: u1, u2, u4, u5, u6.

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