BIOL 1090 Lecture Notes - Lecture 1: G1 Phase, Telomere, Mitosis

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Jan. 9, 2017 l1: cell cycle and mitosis: mitotic cells in the adult would be considered stem cells. 3. facilitate replication of the ends of the linear. Haploid (n) vs diploid (2n) vs dna content (c) Note: mitosis will never produce a haploid cell. Mitosis in animal cells: when mitosis begins, each chromosome has been duplicated and the chromatids are held together by cohesion, centrosome is duplicated at end of interphase. Prophase: initiation of spindle formation, condensation of duplicated chromosomes, fragmentation of er and golgi, nucleolus disappears, nuclear membrane starts to break down, spindle microtubules invade nuclear space. Prometaphase (b/w step 2 and 3 on above diagram: chromosomal microtubules attach to kinetochores, which are on outer surface of centromeres, chromosomes move towards equator of spindle. Metaphase: duplicated chromosomes are aligned midway b/w spindle pores. This equatorial plane is called the metaphase plate: nuclear membrane broken down.

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