BIOC 4580 Lecture Notes - Lecture 19: Monomer, Micelle, Taxus Brevifolia

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Today"s material not covered very well in textbook. The biogenesis, shape, structure, and dynamics of cellular membranes are all facilitated by cytoskeletal proteins that can interact with peripheral and/or integral membrane proteins. The 3 major cytoskeletal protein families are microfilaments, microtubules, and intermediate filaments, all with a variety of accessory proteins. Fluorescence microscopy is a major tool for visualization of cytoskeletal dynamics in living cells. An interlocking 3-d scaffolding that extends throughout the cytosol and interfacing with the pm. Modulation of cell shape and cell movement. The 3 families of cytoskeletal proteins vary in composition and thickness: microfilaments. Actin (eukaryotic protein; there is a bacterial homologue mreb) Actin ~10% of total eukaryotic cell protein. Mfs bound to specific membrane proteins lie just beneath & parallel to pm cortex is underlying layer of cytoplasm. Major property is the cortical actin, just under the pm, maintaining cell structure & shape. Pseudopodia formed by actin pushing the membrane forward.

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