BIOC 2580 Lecture Notes - Lecture 3: Deprotonation, Glutamine, Covalent Bond

• School: University of Guelph
• Department: Biochemistry
• Course: BIOC 2580
• Professor: Enoka Wijekoon

Document Summary

Moderately non-polar: gly, cys, pro, tyr, trp. Has a single h atom as side chain, not enough to be very non-polar. Hydrophobicity is related to the number of ch, ch2, or ch3 groups present. Cys = cysteine contains the slightly polar sh group. Pro = proline is unique because the side chain links to -n as well as -c the polar n moderates the non-polar hydrocarbon. Has a single polar group that partly offsets the very non-polar benzene ring. Amino acids with polar uncharged side chains ser, thr, asn, gln serine and threonine have side chains that include the polar hydroxyl group -oh (simple alcohol) Asn and gln both contain the polar amide group these side chain groups do not gain or lose h+ in aqueous solution at ph7, so they are uncharged. All four side chains act as good hydrogen bond donors or acceptors. Hydrogen bonds are electrostatic attractions between a h-bond donor and an acceptor.