BIOC 2580 Lecture Notes - Lecture 2: Arginine, Glutamine, Hydrophobe

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What best describes electronegativity: the tendency of an atom to attract or hold electrons. The side chains are dominated by hydrocarbon and consist of c-c and c-h bonds. Hydrocarbon is non-polar and hydrophobic (or water avoiding) Polarity is a consequence of atoms having different electronegativity or tendency to hold bonding electrons. Oxygen is the most electronegative, carbon and hydrogen have almost the same electronegativity. Atoms with similar electronegativity share bonding electrons equally eg. c-c, c-h, and are non- polar. Pairs of atoms with different electronegativity distribute bonding electrons unequally - more electronegative atoms such as o or n get greater than 50% share and this leads to unbalanced charges and polar bonds. Glycine has single h atoms as side chains, not enough to be very non-polar. Hydrophobicity is related to the number of ch, ch2 or ch3 groups present. Cysteine contains the slightly polar sh group.

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