BIOC 2580 Lecture Notes - Lecture 1: Coenzyme Q10, Chloroform, Very Low-Density Lipoprotein
21 Oct 2016
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Document Summary
*note; free fatty acids present in very small quantities. Structurally diverse but not defined by chemical structure. Organic solvents dissolve lipids (2:1 mixture of chloroform and methanol) Lipids covalently link to other classes of biomolecules . Glycolipids = sugar and lipid = important constituents of cell membranes i. e antigens on blood groups. Lipoproteins = plasma lipoproteins ( hdl, ldl, vldl) associated with cardiovascular health and disease. Carboxylic acids with hydrocarbon chains ranging from 4-36 carbons. One or more double bonds in chain. Labeling fatty acids number 1 is assigned to carboxyl carbon and alpha to the carbon next to it. Double bonds in pufa are methylene-bridged not conjugated. Double bonds are separated by a methylene carbon so bond pattern = double-single-single-double. Isomerized double bonds of unsaturated fatty acids via partial hydrogenation. Trans double bond (h atoms on opposite sides) Polyunsaturated (pufa) = more than one double bonds.
