ANSC 3080 Lecture Notes - Lecture 19: Carbamino, Bicarbonate, Cyanide Poisoning
27 Mar 2018
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Most of the oxygen in blood (>97%) is reversibly bound to hb as reserve. Henry"s law: amount of gas dissolved is directly proportional to partial pressure of that gas. However, solubility of o2 very low in aqueous solution. At a usual arterial pressure (100mmhg): 3 ml of o2 per l of blood is dissolved. Inreality blood leaving the lungs contains about 200ml o2 per liter (197ml/l bound to hb) There is not a lot of o2 dissolved in blood. If o2 is carried on as dissolved in blood, the blood will not be enough to carry o2 to supply an animal at demanding situations such as during exercise. A greyhound consumes 125ml at rest, 4500ml during exercise per minute. 4 heme groups, each bound to one iron atom (4 o2 molecules) Oxygen saturation is the amount of oxygen carries divided by the total oxygen capacity of blood. % saturation = amount o2 bound/ max capacity.
