ANSC 2330 Lecture 17: Lecture 17 – Respiratory Pathology and Disease
4 Dec 2017
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Document Summary
Non-specific defense mechanisms: mucus, traps particles, moistens the tissue, specialized proteins enzymes. Mucocilliary apparatus: extends from trachea to terminal bronchioles (upper respiratory tract, specialized ciliated epithelium, beats mucus and trapped debris from terminal bronchioles up to pharynx, moves mucus, double layer of mucus. I(cid:374)(cid:374)er sol" layer (cid:894)su(cid:271)(cid:373)u(cid:272)osal gla(cid:374)ds(cid:895) more fluid: outer gel" layer (cid:894)go(cid:271)let (cid:272)ells(cid:895) - more viscous, poor cough mechanism. Immune response: humoral b lymphocytes produce antibodies, cellular t-lymphocytes stimulate b-cells and kill cells and kill cells presenting antigen. Antigen any chemical or protein compound that stimulates an immune response. Primary and secondary immune responses: genetically determined, secondary immune response, greater and faster. Adjuvant non-specific areas of the immune system, this will hopefully increase the response. Usually destroyed by the stomach as the stomach absorbs amino acids, sugars and carbohydrates. Equine respiratory diseases: recurrent airway obstruction (rao or heaves) Average age of onset is 9 years.
