PSYC 375 Lecture Notes - Lecture 17: Reuptake, Morphine, Dynorphin

• School: University of Calgary
• Department: Psychology
• Course: PSYC 375
• Professor: Simon Spanswick

Document Summary

Cross-tolerance- reduction of response to a novel drug because of tolerance to a chemically related drug. In regards to barbiturates and alcohol, there is cross-tolerance because both substances have binding sites on the gaba receptor. Range of physical and intellectual impairments observed in some children born to alcoholic parents. Psychosis includes behavioral disorders such as schizophrenia. Dopamine hypothesis of schizophrenia- dopamine plays a role in the disease, specifically an excess of dopamine activity. The goal of the antipsychotic drugs is to reduce the effects of dopamine. In addition to amphetamine, other drugs can produce schizophrenic-like symptoms. Pcp and special k block glutamate receptors. All three of these drugs can elicit schizophrenic-like symptoms. Major depression- prolonged feelings of worthlessness, guilt, disruption of eating, sleep, slowing of behavior, frequent thoughts of suicide. Over their lifetime, 30% of people will experience a major depressive episode. Higher in northern climates, suggests a relationship between vitamin d and depression.