PSYC 375 Lecture Notes - Lecture 22: Magnetic Resonance Imaging, Receptor Activated Solely By A Synthetic Ligand, Optogenetics

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Optogenetics- transgenic technique that combines genetics and light to control targeted cells in living tissue. Chemogenetics- transgenic technique that combines genetics and synthetic drugs to activate targeted cells in living tissue. Dreadds- designer receptor exclusively activated by designer drugs. Insert a receptor that responds to a biologically inert substance. Eeg measures the summed graded potentials from many thousands of neurons. Depolarization at one end of a cell body leads to extracellular currents that can be measured at the scalp. An eeg recorded from the cortex displays an array of patterns, some of which are rhythmical. The living brain"s electrical activity is never silent, even when the person is asleep or comatose. Eeg provides us with a useful tool for diagnosis of brain abnormalities such as epilepsy. Eeg can be used for research purposes. Event related potentials (erps)- brain activity in response to a discrete stimulus. Eeg activity of the brain after a tone is played.

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