NURS 498 Lecture Notes - Lecture 6: Diabetes Mellitus Type 1, Enteropathy, Hypoprothrombinemia
20 Feb 2018
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Document Summary
Autoimmune disease of small intestine (elithelium) when gluten is digested. Gluten (gliadin) is found in wheat, rye, barely and oats. Gluten introduced to genetic- susceptible pt activation of t h cell, antibody, complement atrophy, flatten of villi + crypt elongate decrease sa of villi + crypt become hyperplastic malabsoprtion. Destruction of mucosal cells inflammation diminished secretion of intestinal hormones (secretin/ cholecystokinin) + water/electrolyte secreted malabsoprtion + watery diarrhea + fatty stool. *secretin water/bicarb from pan into duodenum *cholecystokinin bile from gall/digest enzymes from pan. Bm/day) pale, bulky, greasy, foul smelling, contain oil droplets. Fail to thrive abdominal protuberance, wasted buttocks, limbs, hypotonia. Rickets (bone disorder), tetany, frank or occult blood or anemia. Hypmagnesaemia/calcemia irritability, tremor, convulsions, tetany, bone pain, osteomalacia, dental abnormalities. Dehydration (skin tigour, ins/outs, mucus membrane, thirst, specific urine gravity) Avoid wheat, barely, oats, rye, meds, foods that contain gluten. Colitis around mouth) + anemia + smooth, red tongue (glossitis)
