KNES 323 Lecture Notes - Lecture 8: Central Chemoreceptors, Respiratory Center, Peripheral Chemoreceptors

• School: University of Calgary
• Department: Kinesiology
• Course: KNES 323
• Professor: Carol Gibbons Kroeker

Document Summary

Depends on surface area, solubility, membrane thickness, diffusion distance, concentration gradient (most important). Majority of air (~79%) is nitrogen, the rest is oxygen, co2, and other randoms. P. gas = p. atm x % of gas in atmosphere. Alveolar ventilation is inadequate. (low lung compliance, high resistence) Anemic hypoxia- low amount of oxygen bound to hb. Oxygen diffuses across alveolar epithelial cells and capillary endothelial cells to enter blood plasma. Larger oxygen pressure (like that in the alveoli) have a very high hb saturation %. Hb saturation decreases at an accelerated rate as oxygen pressure drops. Physiological factors such as high temp or exercise shit the curve to the right, which is good because it represents a greater ability to unload and use the oxygen. Oxygen is still consistently loaded, but the dissociation and use rate increases. Summary of oxygen and carbon dioxide exchange and transport: A shift left is usually bad, unless you are pregnant.