CMMB 431 Lecture Notes - Lecture 25: Pilus, Serotype, Pseudomonas

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Efp protein: translation factor, comes into ribosome and activates it again. Has 2 membranes (ir gram negative), and a agella (useful because it lives in water), facultative anaerobe (can live in intestines as well) Vibrio means comma, de nes the shape of the bacterium. Causal organism of cholera, which is sometimes deadly. Disease causes lots of water diarhhea and vomiting. Endemic in many parts of the world, speci cally developing world. Currently the most cases is us, and the current number is 190 000 (covid-19) Mortality rate for covid-19 is also 1-5% Cholera is a pandemic disease, so it works in a lot of outbreaks. Bene cial thing from outbreak: work of john snow. At the time, the general theory was miasma theory, where people thought disease probably just came from bad air. John snow wanted to provide evidence against miasma theory. He walked door to door and asked people if they had cholera.

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