PHYSL210A Lecture Notes - Lecture 2: Blood Vessel, Sunburn, Anatta
Document Summary
Following topics: inflammation, purpose of inflammation, physical characteristic of inflammation, changes in vasculature (blood vessel wall, features of acute (short-term inflammation) Inflammation: cell in the body is protected by barrier. The resulting barrier injury result in inflammation: non-specific innate response to tissue injury initiates inflammation. Injury will lead to inflammation: purpose of inflammation, healing/ resolution, destroy non-self agent, scar tissue developed: fibrosis. Inflammatory has 3 components: inducer sensors mediators, inducers: causative agent, initiate inflammatory response, sensor: sense the present the foreign agent and activate mediators, mediators: take over the task of repair. Inflammation is associated with poor physical or cardinal signs: redness (rubor, swelling (tumor, heat (calor, pain (dolor, loss of function, these support the process of inflammation. Increased blood flow: histamine causes expansion of blood vessel and blood flow, associated with redness and heat, Allow protein to move out to the extracellular space. Cause fluid to move out (sweling in the area)