PHYSL 210 Lecture Notes - Lecture 11: Reabsorption, Arteriole, Sodium-Glucose Transport Proteins

• School: University of Alberta
• Department: Physiology
• Course: PHYSL 210
• Professor: Sashwati Das

Document Summary

3 basic renal processes: filtration, secretion, reabsorption, enter into lumen, filtration (directly from glomerulus, secretion (enter from arterioles, exit out of lumen, reabsorption (back into lumen, excretion of urine (shit thats left) Glomerular filtration: net glomerular filtration is always positive, pgc forces protein-free filtrate from plasma out of the glomerulus into bowman"s space, bowman"s space has no protein. Increased tubular flow due to increase gfr causes constriction of afferent arteriole in order to reduce gfr: regulated by paracrine actions on juxtaglomerular apparatus, mean arterial pressure - average blood pressure of an individual in one cardiac cycle. Gfr regulation (not autoregulation: myogenic response, similar to autoregulation in other systemic arterioles, tubuloglomerular feedback: a role for juxtaglomerular apparatus (jga) Increased tubular flow due causes constriction of afferent arteriole in order to reduce gfr: regulated by paracrine actions on juxtaglomerular apparatus, hormones and autonomic neurons (main diff between autoregulation and regulation, by changing resistance in arterioles.