NURS406 Lecture Notes - Lecture 11: Diabetes Mellitus Type 1, Blood Glucose Monitoring, Diabetes Mellitus Type 2
20 Jun 2020
School
Department
Course
Professor
Document Summary
Insulin also inhibits the breakdown of stored glucose, protein and fat. Combined genetic, immunologic and possibly environmental (ex. viral) factors contribute to beta cell destruction. They do not inherit type 1 diabetes, but a genetic predisposition: human leukocyte antigen (hla) types, 95% of whites with type 1 diabetes have hla types (dr3 or dr4) Concentration of glucose in the blood exceeds the renal threshold for glucose, usually 9. 9 to. 11. 1 mmol/l, the kidneys may not reabsorb all of the filtered glucose; the glucose then appears in the urine (glucosuria) Excess glucose is excreted in urine, it is accompanied by excessive loss of fluids and electrolytes, called osmotic diuresis. When there is a deficiency in the presence of insulin, the stored fat is broken down to provide a source of energy, resulting in the production of ketone bodies, which can lead to the development of ketosis. Onset of type 1 diabetes is more abrupt.
