NURS305 Lecture Notes - Lecture 2: Inflammatory Bowel Disease, Budesonide, Thrombosis
Document Summary
Drug name: sulfasalizine (azulfidine) - for mild to moderate inflammation. In diabetic patients, monitor glucose levels closely as it can cause an altered effect of oral hypoglycemic agents. Drug name: hydrocortisone, prednisone, budesonide - po for severe disease, topical (rectal) for distal colon disease. Dose: hydrocortisone (20-240 mg/day), prednisone (5-60 mg/day), budesonide (9 mg/day for active cd, 6 mg/day maintenance) Side effects: depression, hypertension, peptic ulceration, thrombic embolism. Nursing implications: educate patient to monitor weight and report excessive gains/losses, signs of infection, or visual changes. Drug name: azathioprine (imuran) - alters immune response. Dose: 2. 5 mg/kg po or iv per day. Nursing implications: instruct patient to avoid breastfeeding; report symptoms of fever, chills, shortness of breath, chest pain. Drug name: anti-il-12 ustekinumab (stelara) - anticytokine therapy. Dose: begin with iv infusion, then 90 mg sc every 8 weeks for maintenance.
