NURS113 Lecture Notes - Lecture 9: Dysuria, Clinical Urine Tests, Cauterization
5 Dec 2017
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Chronic kidney disease (dialysis required: decreased function or kidney damage of three months" duration, diagnosis: gfr<60 ml/min for three months with or without kidney damage. ** normal: male: 125 ml/min; female: 120 ml/min: pathogenesis: progressive and irrevocable loss of functional nephrons. Stage1 &2: focus on minimizing risk factors (asymptomatic) ///dht (dihydrotestosterone) is the mediator that convert androgen to estrogen, which increase the sensitivity of prostate tissues to the effect of dht: pathogenesis: enlarged prostate in the peri-urethral zone. ***psa: prostate specific antigen only used as a screening tool, cannot distinguish between benign and cancer only tells you size (bigger psa // Cancer of the prostate (not all aging men get this: causes: dietary factors (high dietary fat intake increase risk) ///chemoprevention (use drugs to prevent) with the 5 - reductase inhibitor. !> ///finasteride (5 -reductase inhibitor) **5 -reductase is an enzyme that converts testosterone to 5 hydrotestosterone, which makes prostate more sensitive (more potent).
