NURS 216 Lecture Notes - Lecture 27: Adipose Tissue, Adipocyte, Adipokine
3 Feb 2020
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Fat: macronutrient (9 cal/kg) testosterone and estrogen control where fat is located. Function: thermogenesis for insulation, insulin sensitivity and glucose tolerance. More similar to skeletal tissue than white adipose tissue. Declines due to the increase levels of hormones (e. g. testosterone) Function: energy (uptake of excess glucose), storage (triglycerides) insulation, protects organs. Kidney adipose tissue is the last to break down when body requires energy stores. Endocrine organ, storing over 90% of the body"s energy cache. Highest percentage found in obese, female and elderly individuals. Release: metabolism of triglycerides into components 3 fatty acids & glycerol (yields glucose) Adipokine secretion leptin (satiety regulation) adiponectin cytokines (interleukins, growth factors) Triggers feelings that an individual is full, but in obesity it can cause feelings of perpetual. Increased wat decreased leptin bbb distribution & receptor binding (increases. Total numbers of leptin are elevated alternate binding sites proinflammatory mediation + degradative connective tissue enzymes.
