NURS 216 Lecture Notes - Lecture 22: Sepsis, Sertraline, Risperidone
11 Jan 2020
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Serotonin: inhibitory affects excitation and mood balance used to enhance mood. Nmda agonisten treatment of depression decreases excitability of cells by increasing chloride influx. 1st line treatment: cbt - cognitive behavioural therapy (e. g. biofeedback) Signs & symptoms (can be positive or negative) Mental health illnesses: bipolar disorder, severe depression. Overstimulation in hospital environment (isolation and decreased stimulation areas used for treatment) D2 (dopamine) receptor blocker in the limbic system (not addictive, wide ti, high ppb) Haloperidol (haldol) associated with 5ht blockade anticholinergic sedative onset of action: 6-8 weeks for overall improvement stop treatment slowly to prevent delirium tremens chronic treatment is required to most patients anticholinergic side effects: urinary retention, dry mouth, sexual dysfunction. Neuroleptic malignant syndrome toxic reaction: hyperthermia, unstable bp, diaphoresis, incontinence no interaction with dopamine depot shots provide better adherence. D2 antagonist in basal ganglia extrapyramidal side effects tardive dyskinesia (tongue movement) parkinsonism (rigidity) tremors restlessness dystonias (muscle spasm) Incomprehensible speech: invented words, disconnected words & thoughts.
