NURS 116 Lecture Notes - Lecture 14: Peptic Ulcer, Opisthotonus, Neisseria
1 Mar 2019
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Document Summary
Meningitis - condition characterized by the inflammation of the meninges, which are the fluid filled membranes that cover the brain and spinal cord, most commonly caused by bacteria or viruses. Sleepiness or unable to fully wake up. Opisthotonos - severe stiff neck characterized by arch. Bulging of the fontanelles (soft spots in the baby"s skull) Vancomycin + 3rd generation cephalosporin : 2-50 years (greater than 50 adds ampicillin) and. Basilar skull fractures as a result of s. pneumoniae, n. meningitidis etc. Vancomycin + cefepime or ceftazidime: penetrating trauma, post neurosurgery and csf shunt as a result of s. aureus, pseudomonas etc. Prevents the emergence of resistance to individual agents. Inhibits transpeptidase , inhibiting synthesis of the peptidoglycan wall. Increased risk of diarrhea compared with amoxicillin. Can lead to opportunistic yeast infections,increased level of eosinophils. Destroyed by beta lactamase (a prep with clavulanic acid is available) *most options in the penicillin family share very similar features and are not overly specific.
