NURS 116 Lecture Notes - Lecture 11: Goblet Cell, Mast Cell, Secretion
Document Summary
Ige mediated inflammatory response degranulation of mast cells histamine release inflammatory cell infiltration. Goblet cells - found in respiratory and gi tracts, main mucous secretory cell. Decreased mucociliary transport (cough, spit and swallow mucus on an ongoing basis) Leads to more mucosal shedding, which then leads to luminal narrowing to begin the. Anti-inflammatory agents - corticosteroids, chromones, lukasts, 5-lox inhibitor, antihistaminiques, Miscellaneous - mucolytics, antibiotics, monoclonal antibodies, desensitization management) (sama) creates direct stimulation of bronchodilation. Treatment depends on goal ( prevention such as chronic conditions or immediate symptom. Reliever - short acting beta 2 agonists (saba) , methylxanthine, short acting anticholinergic. Controller - last lasting beta 2 agonist (laba), inhaled corticosteroids, methylxanthine. The least medication to regain and maintain control. Multi-dose administration for relievers: causes rapid heartbeat, restlessness, fatigue, vasoconstriction (same as you would with a spike in the sympathetic nervous system) Nebulizer - device used for fine spray of liquid. Inhaled preparations used for health conditions affecting lungs.