MMI133 Lecture 5: Session 5 Virus

• School: University of Alberta
• Department: Medical Microbiology and Immunology
• Course: MMI133
• Professor: Judy Gnarpe

Document Summary

Desti(cid:374)ed to drift i(cid:374) spa(cid:272)e u(cid:374)til it (cid:272)a(cid:374) do(cid:272)k (cid:449)ith the appropriate (cid:862)(cid:373)other-ship(cid:863) (cid:894) host (cid:272)ell(cid:895) a(cid:374)d offload cargo. Cargo = viral genome takes over the host cell machinery and produces many (cid:862)(cid:272)lo(cid:374)es(cid:863) (cid:894)(cid:374)e(cid:449) viruses) New viruses leave the host cell and drift, looking for their own host cells to infect, sometimes take a souvenir coat when they leave the host cell. Responsible for majority of visits to family physician. Many ways they can be transmitted from host to host: e. g. blood transfusion, mucus droplets, aerosols, fomites, water, food, vectors. Must be treated using different therapeutic strategies than other microorganisms because they are different in makeup and structure. No ribosomes or enzymes for metabolizing nutrients. Most are free-living and multiply outside of host cells. Contain ribosomes and enzymes for metabolism of nutrients. Virion: complete infectious viral particle with nucleic acid surrounded by a protein coat. Rna or dna (cid:894)ss or ds(cid:895) + (cid:862)(cid:272)apsid(cid:863) (cid:894)protei(cid:374) (cid:272)oat(cid:895) (cid:272)o(cid:373)prised of: (cid:862)(cid:272)apso(cid:373)eres(cid:863) (cid:894)protei(cid:374) (cid:373)ole(cid:272)ules(cid:895)