MMI133 Lecture Notes - Lecture 4: Anaerobic Respiration, Cellular Respiration, Bacterial Growth

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Endotoxin: ie lipid a in lps (stim the immune system) Part of the cell structure anchored in outer membrane. Released from the cell when it dies (when cell wall disintegrates) Produced by the bacterial cell (ribosomes synthesize); not part of cell structure. Released from cell in many ways, damages other cells (very potent) 3 types: enterotoxin, neurotoxin and cytotoxin (depends on where they act) Describe how bacterial metabolism has an effect on rate of growth. Explain the growth requirements of bacteria (nutrient, gaseous, ph, temp) Id listeria monocytogenes as a prob for food borne infection and describe its characteristics and pathogenesis. Define the kinetics of bacterial growth: metabolism. Metabolism: sum total of all chemical rxns w/n organism. Catabolism: chemical rxns that release energy, breakdown of organic compounds. Enzymes e. g. glucose carbon dioxide + water. Chemical rxns that require energy, building of complex organic molecules from simpler compounds (stores atp) Ie formation of polysaccharides from simpler sugars like glycogen from glucose.

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