IMIN200 Lecture Notes - Lecture 7: Innate Immune System, Adaptive Immune System, Cytopathic Effect

• School: University of Alberta
• Department: Immunology and Infection
• Course: IMIN200
• Professor: Mario Feldman

Document Summary

Acute infection - determines if you live or die. But even 1 particle can initiate a round of replication - then you"ll get an immune response. If virus have gone thru a round of replication. Provides with a life long immunity to virus. Very specific for that virus interferon production only on the first part very limiated to the early response. Time course of an innate immune response to a virus. time course. Virus get sin exponentially replicting - happens rapidly (1-2 days) All happens on day 1 of innate response. Nk cells come in and clean up viral cells (day 2) Happens at day 3, for sure day 7. Very efficient with getting rid of virus innate response - interferon response. If no if, then virus will replicate 1000x faster. The course of an acute infection-rapid and self limiting. Brackets indicate infectious virus present many virus are acute infections. Hit and run viruses, get infected, replicates, lyse cell.