IMIN200 Lecture Notes - Lecture 8: Antigen Presentation, Apoptosis, Antigen

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Cytotoxic t cells must be activated to become effectors. Time of innate and adaptive immune responses to acute viral infections not started til day 4-5 and continues to kill for about a week and then clears the virus. Ctl killing of infected cells takes about a week. Defense against intracellular pathogens by cytotoxic t lymphocytes. Cytotoxic t-cell (t) coming in for the kill (v - virally infected target cell) Cytotoxic t cells kill intracellular pathogens, by killing the infected cell. After it joins the membrane with all of the proteins in the interaction - takes about a minute. Really difficult to pull the cells apart after this point. Even though they are close to other cells, will only kill the specific one it is interacting, not the neighbour close ones. Cytotoxic cell killing by delivery of a signal inducing death. physically pulling the 2 cells apart. Ctl kill by apoptosis (forced cell suicide) kills by:

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