BIOL207 Lecture Notes - Lecture 7: Mutagen, Missense Mutation, Histidine
25 Sep 2013
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When it comes to mutation caused by base pair mutations, keep in mind that single base substitutions are extremely more likely than 2+ bp substitutions. So much more likely that figuring out how many ways you can get a histamine from an arginine is just dependant on how many possible single bp substitutions are needed only. (2 possible ways) What does mutation do to a gene: neutral or no effect", hypomorph = decreased amount/activity of protein, amorph = protein is not made at all or is totally useless. Genotype = genes and alleles already in an organism. Phenotype = visible characteristics of an organism. Genotype + environment = phenotype: nature + nurture. Neurospora with arg- gene has 2 possible phenotypes: In absence of arginine, phenotype = no growth. Another example is curly winged fruit flies: having the gene for curly wings it not enough.
