BIOL201 Lecture Notes - Sickle-Cell Disease, Hbb, Allele Frequency

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burgundyoyster582

11 Apr 2014

School

University of Alberta

Department

Biology (Biological Sciences)

Course

BIOL201

Professor

Michael Harrington

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Document Summary

Biology 207 - practice questions 10 - population genetics. Question 1 in a wild population of sneetches you notice that 2/3 of the sneetches have stars on their bellies and 1/3 do not. Question 2 both of the populations of flowering plants i used in class were in hwe. In this field there are 116 red, 211 pink, and 173 white plants: is this population in hwe, assuming random breeding, no selection, etc. Question 3 hemoglobin, the oxygen transporter found in red blood cells is made of two alpha globin and two beta globin proteins. The glu6val mutation in the hbb gene makes a defective beta globin protein. People heterozygous for this mutation are said to have sickle cell trait while people homozygous for this allele have sickle cell disease. It is common to refer to this mutant allele as hbbs for this reason.

Related Questions

1. If an individual has a genotype of Bb, what types of gametes (sperm/egg) could they produce?
A) B
B) b
C) B or b
D) Bb, BB, bb
E) Bb

2. Which of the following statements is true about phenotypic plasticity, i.e., phenotype variation that is the result of genotype by environment interactions?
A. Phenotypic plasticity is only favored when the parental environment is a good predictor of the offspring environment
B. Since the trait expression of a genotype varies across environments, it cannot respond to selection
C. A variable environment is required for phenotypic plasticity to be selected for
D. A single trait can only ever be plastic or non-plastic within a species
E. Phenotypic plasticity can only occur within a single generation, never across generations

3. With large numbers of genes contributing to variation for a phenotypic trait (e.g. height in humans), the population approaches what kind of distribution for that trait?
A. Mendelian
B. Exponential
C. Binomial
D. Normal
E. Continuous

4. A classic example of phenotypic plasticity is caste determination in social insects. Whether a female ant becomes a worker, soldier, or queen is determined by the food she is fed. Would you say this this an example of G, E, or GxE?

5. In an infinite population, the frequency of the A allele is 0.3 and the frequency of the a allele is 0.7. What is the frequency of heterozygotes?
A. .10
B. .21
C. .30
D. .42
E. .70

6. Blue eyes are a recessive trait caused by an autosomal allele. If there are 180 people with blue eyes in a population of 500 people, what is the frequency of the brown-eye allele? (Assume HWE)
A. .36
B. .40
C. .50
D. .60
E. .64

7. Imagine flower color in diploid roses is determined by a single gene with two alleles, white and red, which are co-dominant so that heterozygotes are pink. Frank is colorblind and can only discriminate between white and colored roses, and knows that his population has 18 white roses and 182 non-white roses. How many of Frankâs roses are pink? (Assume HWE.)
A. 18
B. 21
C. 42
D. 84
âE. 100

8. Imagine flower color in diploid roses is determined by a single gene with two alleles, white and red, which are co-dominant. If Eva's population has 250 white roses, 500 pink roses, and 250 red roses, what is true about this population?

A. It is not in Hardy-Weinberg equilibrium
B. It is under balancing selection
C. It is connected to another population by migration
D. It is in Hardy-Weinberg equilibrium
ââE. White is a recessive lethal

9. 9% of a population is unable to taste the compound PTC, which is a recessive trait. Assuming HWE, if two carriers of the non-tasting allele had a baby what is the probability that it would be unable to taste PTC?
A. 0.09
B. 0.25
C. 0.30
D. 0.50
E. 0.70

10. (Adapted from: Christensen, A. C. (2000). Cats as an aid to teaching genetics. Genetics, 155(3), 999-1004.) ss cats have no white fur, Ss cats generally have <50% white fur, and SS cats generally have >50% white fur (cats who are 100% white are scored as dominant white and can't be scored for piebald spotting). The S allele is incompletely dominant, but variably expressed, so there is a more-or-less continuous gradient of white pigmentation in populations. You and your friends score all non-white cats up for adoption: http://www.adoptapet.com/cat-adoption/search/50/miles/48824 and find there are 160 with >50% white fur, 350 with <50% white fur, and 490 with no white fur. Which of the following statements is definitely true:

A. The population is in Hardy-Weinberg equilibrium
B. The population is not in Hardy-Weinberg equilibrium
C. There is selection acting on the population
D. It is impossible to know if the population is in Hardy-Weinberg equilibrium
E. Fur color is not a heritable trait and therefore cannot evolve

tanbadger837

A population of wild-flowers was scored for flower color. There were 369 blue (BB) plants, 1915 violet (BR) plants and 748 red (RR) plants. Please round your answer correctly to 4 decimal digits.

1. What is the frequency of the blue (B) allele?

2. What is the frequency of the red (R) allele? Please round your answer correctly to 4 decimal digits.

3. A chi-square test was conducted to test the hypothesis that the population genotypic frequencies are consistent with Hardy-Weinberg equilibrium frequencies.Fill in the spaces below with the expected numbers for each phenotypic (genotypic) class in the chi-square test. What is the expected number of blue (BB) plants? Please round your answer correctly to 4 decimal digits.

4. What is the expected number of violet (BR) plants? Please round your answer correctly to 4 decimal digits.

5. What is the expected number of red(RR) plants? Please round your answer correctly to 4 decimal digits.

6. Keeping all decimal digits during your calculations and rounding your answer to 3 decimal digits, what is the calculated chi-square value?

True breeding whilte flowering plants are crossed to true breeding red flowering plants. the offspring are red flowered. when these flowers are self crossed, the resultant offspring are 92 red, 57 pink and 12 white flowered plants. which of the folloeing pathways is most likely the cause of this?

A. white --A-> pink--B-->red

B. pink --A-->pink--B-->red

C. red <--A--white--B-->red

D. white --A--> pink white --B-->pink both genes producing pink together give red (this is the correct answer) but why>?

can someone explain what are pathways how do i tackle a question like this? i know the right answer but cannot understand why this is a practice quetsion and nothing in my book explains how to do this

BIOL201 Lecture Notes - Sickle-Cell Disease, Hbb, Allele Frequency

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