BIOCH200 Lecture Notes - Lecture 23: Metabolic Pathway, Exergonic Reaction, Blood Sugar

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Biochem 200 - lecture #23 - introduction to metabolism. Metabolic pathways: enzyme catalyzed, chemical reactions that are connected, metabolites are chemical intermediates, shared between organisms and cell types. Eg. liver vs skeletal muscles: all pathways share the same fundamental chemical and thermodynamic principles, pathways are always falling towards equilibrium, anaplerotic reaction: replenish metabolites removed from central metabolic pathway. 2 major purposes of metabolism: obtain usable chemical energy from the environment. Consume and breakdown nutrient molecules: make specific molecules that cells need to live and grow. Metabolism overview: anabolic pathways: use energy to build larger molecules and are. Electrons used to make new bonds: catabolic pathways: release energy to breakdown into smaller molecules and are oxidative. Electrons are removed as bonds are broken: amphibolic. Dietary macromolecules: nucleic acids - not a significant fuel source. Can be used to resynthesize: polysaccharides (complex carbohydrates)

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