NURS 3550H Lecture Notes - Lecture 10: Mydriasis, Phenylephrine, Salbutamol
31 Oct 2018
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Prototype = norepinephrine stimulates 1 / 2 best limited therapeutic value. Want 1 effects: shock, produce vasoconstriction. Therapeutic indications: nasal congestion (otc preparations, maintain bp, paroxysmal (in bunches) supraventricular tachycardias, mydriasis (needed for some kind of eye surgery, shock (bp drops therefore this helps to boost bp) Bradycardia (reflex) cocaine can actually make your heart slow down too much. Drugs that / ne levels. Drug that alter hr (especially drugs that slow down hr) Cerebrovascular disease (^ pressure on a soft pressure in the brain and rupture) Glaucoma (can increase intraocular pressure due to vasoconstriction and mydriasis) Benign prostatic hyperplasia aka bph (prostate enlarges but it is not cancer: only in men, risk ^ as you age. Prototype = isopropylnorepinephrine stimulates 1 and 2 r limited uses. Mechanism - stimulates 1 r, d r, 1 r dose-response. 1 r at high dose stimulates 1 r. Kidney ^ renin release stimulates d r. Dilation of renal vasculature stimulates 1 r.
