PSYC 381 Lecture Notes - Lecture 3: Pregnenolone, Mineralocorticoid, Steroid

• School: Simon Fraser University
• Department: Psychology
• Course: PSYC 381
• Professor: Neil Watson

Document Summary

Cholesterol prenenolone (all steroids derive from these 2) . Mineralcorticoids not super important for our purposes. Can"t concert 17 and dht into eachother though. Main estrogen in regards to behaviour = 17 (aka e2) All estrogens made from androgens through aromatization (within ovaries in females) Important for female sexual behaviour: forms of aggression/other feminized behaviours, masculinization of brain structures and behaviours. Work differently than neurotransmitter receptors: *remember steroids are lipid soluble, and cell membranes are lipid bilayer so steroids easily diffuse across membrane. In cytoplasm: bound to nucleus (estrogen receptors) ** non-canonical types of steroid receptors are membrane-bound and have comparatively rapid non-genomic effects, Insulin/ glucagon: adrenocorticotropic hormone (acth, releasing hormones, also know the basics of prohormones like pomc. Amine hormones: modifications of single amino acid molecules (smallest hormones: epi ad ne, da, thyroid hormones (thyroxin) = fat soluable, melatonin/5ht, others!!