HSCI 212 Lecture Notes - Lecture 11: Sylvatic, Yellow Fever, Apoptosis

• School: Simon Fraser University
• Department: Health Sciences
• Course: HSCI 212
• Professor: Robert Hogg

Document Summary

Arbovirus: distribution patterns driven by presence or absence of vectors, also based on origins of the virus, yellow fever has a sylvatic and urban cycle, have great vaccine - expensive - has to be kept cold. Dengue: don"t have drugs to get rid of it, have vaccine, have four different types of dengue, challenge: need vaccine that"s tetravalent - but not working, if those parasites make us sick - the vector doesn"t care. If too large for phagocytosis - get melanonic encapsulation. Intracellular not responsive to immune response - apoptosis: dengue turns on iap1 - inhibitor of apoptosis.