BISC 313 Lecture 17: EDC part 1-2

• School: Simon Fraser University
• Department: Department of Humanities Biological Sciences
• Course: BISC 313
• Professor: Vicki Marlatt

Document Summary

Lecture 12 intro to endocrine disrupting substances. What is endocrine disruption: endocrinology basics, endocrine disrupters. Endocrine disrupting substances: overview of primary substances of concern, canadian regulatory efforts and global situation. Endocrine disrupting substances of concern: case studies. Imbalance in steroid levels = adverse effect: i. e. frogs gonadal malformations (ovotestis) several studies from us epa tier 1 endocrine disrupting screening assays alters lh and fsh so effecting hypothalamus or pituitary hormone secretion. Broadleaf weed control on crops: including corn and lowbush blueberries and was detected in 71-75% of waterways sampled in bc. Banned from use in the european union (eu) in 2004 due to persistent groundwater contamination: eu relies on level of 0. 1 ug/l maximum acceptable concentration for any individual pesticide in ground water (precautionary approach, legislated threshold) Atrazine was also briefly banned in bc, but in 2012 was reapproved for use on agricultural crops. Health canada decides not to ban atrazine found in drinking water in canada.