BISC 313 Lecture Notes - Lecture 8: Chain Transfer, Bioaccumulation, Biomagnification

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Major classes of contaminants and pollutants (chemistry, source, effects): 1. Chemical management plan in canada: canada"s domestic substances list, categorization of chemicals (pbt) Polarity: often measured by octanol-water partition coefficient (kow) Kow = concentration of solute in octanol/ concentration of solute in water (kow) is the ratio of a chemical"s concentration in octanol to its concentration in the aqueous phase of a two-phase system at equilibrium. Partitioning between octanol and water in the lab is a model for the partitioning of a xenobiotic between the aqueous and lipid phase in vivo. Higher kow = more lipophilic: very useful parameter in predicting the fate of a chemical in a biological system. Bioaccumulation vs biomagnification: what is persistent, biomagnification: concentration increases as you go up the trophic levels, bioaccumulation: concentration increases within a single species over time. Bioaccumulation = bioconcentration + food chain transfer = (elimination + growth dilution) Bioaccumulation = net uptake (diet, respiratory, dermal absorption) = (elimination + growth dilution)

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