HAP201 Lecture Notes - Lecture 5: Gas Exchange, External Intercostal Muscles, Internal Intercostal Muscles

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Three basic steps to the process of gas exchange in the body. Pulmonary ventilation (breathing: air flow between atmosphere and alveoli due to alternating pressure differences created by contraction and relaxation of respiratory muscles. Internal respiration (gas exchange in tissue: pco2 > po2 tissues o2 unloaded from blood into the tissue, pco2 tissue > pco2 blood co2 diffuses into the blood, passive diffusion of gases based on gradient. Inhalation occurs when alveolar pressure falls below atmospheric pressure. Exhalation occurs when alveolar pressure is higher than atmospheric pressure. Bo(cid:455)le"s la(cid:449: volume of gas varies inversely with its pressure. Differences in pressure caused by changes in lung volume force air into lungs during inhalation and out during exhalation. Contraction of diaphragm and external intercostal muscles increase size of the lungs. Air moves down a pressure gradient from the atmosphere into the lungs.

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