PLN 203 Lecture Notes - Lecture 1: Protein Kinase C, Thyroid, Pituitary Gland

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Document Summary

Regulates long term processes like reproduction, growth and development. Uses chem messengers to give info in between cells. Hypothalamus- brain: produces adh, oxytocin, regulatory hhormones. Pituitary gland: anterior lobe releases acth, tsh, gh, prl, fsh, lh and msh, posterior lobe releases oxytocin and adh. Adrenal gland- epinephrine, norepinephrine: adrenal cortex- cortisol, aldosterone and androgens. Direct communication exchange of ions/molecules across gap junctions: occurs btwn 2 cells of same type, specialized and rare. Paracrine communication- uses chem signals to transfer info (cells within same tissue: most common. Endocrine communication- release hormones into blood: changes metabolic activity. Synaptic communication occurs across a synaptic cleft: che(cid:373) (cid:373)esse(cid:374)ger is (cid:862)(cid:374)eurotra(cid:374)s(cid:373)itter(cid:863, limited to very specific areas (ex:cns) Specific cells that hormones bind to specifically to (cid:271)e a(cid:271)le to get (cid:862)read(cid:863) Stimulates synthesis of enzymes or structural proteins. Circulate freely or bound to carrier proteins: free hormone has a shorter lifespan then a bound hormone (longer half life, greater activity)

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