PAT 20A/B Lecture Notes - Lecture 9: Metastasis, Malignancy, Neoplasm

• School: Ryerson University
• Department: Pathotherapeutics
• Course: PAT 20A/B
• Professor: shirley

Document Summary

Examples: esptein barr virus burkitt"s lymphoma, hpv cervical cancer, hep b virus liver cancer, aids kaposi"s sarcoma *a malignant tumor of blood vessels in the skin caused by immune deficiency that increases susceptibility to viral infection, infection of kshv (kaposi"s sarcoma associate herpesvirus) Stem cell theory: loss of intracellular control of proliferation results from mutation of stem cells, dna is substituted or permanently rearranged, once mutated , cell can die from damage or by initiating apoptosis, can recognize damage and repair itself, survive and pass on damage, surviving mutated cells have potential to become malignant. Differentiate into all specialized cells + normal work: adult stem cells (from various tissues, act as reparative systems in the body, stem cells have 2 properties, self renewal: the ability to go through numerous cycles of cell division while maintaining the undifferentiated state, potency: the capacity to differentiate into specialized cell types.