PAT 20A/B Lecture Notes - Lecture 9: Angiotensin-Converting Enzyme, Juxtaglomerular Apparatus, Blood Vessel
4 Mar 2019
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Document Summary
Humoral mechanisms in bp control: adh (antidiuretic hormone) (vasopressin) increases bp, osmoreceptors sense a decrease in bp due to decreased blood volume, stimulates posterior pituitary to release adh (vasopressin) & causes vasoconstriction. Endothelial cells: present in blood vessels, et (cause vasoconstriction) & nitric oxide (causes vasodilation, when there is a disfunction in these cells they either release more et or the body does not respond to. Hypertension (htn: htn definition bp above normal range, hypertension is a common, often asymptomatic disorder in which blood pressure persistently exceeds. 140 mmhg or diastolic pressure exceeds 90 mmhg: almost canadians have hypertension, worldwide > 40% of adults over 25 years old, note: hypertension canada guidelines committee (hcgc) 2018 replacing canadian hypertension. Education program (chep) guidelines in hannon and porth pg. Is a major risk factor for atherosclerosis since it promotes and accelerates plaque formation and possible rupture. Increase co: as a result of increased fluid retention.
