PAT 20A/B Lecture 5: Week Five- Fluid and Electrolyte
Document Summary
Amount & direction of fluid determined by: capillary filtration (hydrostatic) pressure: Is the pressure pushing water out of the capillary into the interstitial spaces: plasma oncotic pressure: Is the pressure that pulls fluids back into the capillary: interstitial hydrostatic pressure: Is the pressure which opposes the movement of water out of the capillary: interstitial oncotic pressure: Is the pressure which pulls water out of the capillary into the interstitial spaces. Normally these forces result in a minor excess of fluid in the capillary space, the lymphatic system collects this excess fluid & returns it to systemic circulation. Which ions exert main osmotic force: depends on which ion is most abundant in that compartment, for ecf it is na+, for icf it is k, what other factors generate osmotic force, dissolved, impermeable proteins. Mechanisms of edema formation: edema is excessive accumulation of fluid within the interstitial spaces.