FNN 100 Lecture Notes - Lecture 10: Calcium Citrate, Bone Density, Kidney Stone Disease

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Key vit and minerals: ca, p, mg, vit d, vit k, fluorine. Bioavailability- how much of a nutrient is absorbed. Fat soluble vit require fat to be absorbed and protein carriers. Inactive form of vitamin that gets converted to active form in the body. Cofactors and coenzymes: need the vit/min for enzyme to activate. Mainly ca and p hydroxyapatite: contains mg, f, na and other trace minerals too. Bone remodelling: constantly being broken down and reformed growth. Osteoclast break down bone: peak bone mass=16-30yrs. After this is looses mass and density. Osteoporosis: loss of matrix and mineral deposit of bone, loss of total bone density, use dxa (x ray) to measure bone density, t score below -2. 5 sd, lack ca and vit d. Regulatory roles tight range of ca levels. 99% in solid mineral deposit in bone and teeth: 1% in intracellular fluid, blood, and extracellular fluid.

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