BLG 311 Lecture Notes - Lecture 4: Bacteriorhodopsin, Resting Potential, Paramecium
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29 Dec 2017
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Membrane transport of small molecules and electrical properties of membranes. Membrane permeability is inversely proportional to size, polarity, and charge: example water permeates the membrane 109 times faster than small ions. Because ions have an inability to cross the membrane bilayer on their own this dictates that we have to have transport proteins. Hydrophobic molecules can pass through the lipid bilayer easily because they have non-polar groups that are happy being in the hydrophobic part of the lipid bilayer. No transport function needed for this, molecules can take care of themselves. They have a hard time going through the plasma membrane but still leak through every now and then. Harder time going through the plasma membrane because they are big molecules. Molecules that are charges and have a really hard time going through the membrane on their own. Ion concentrations inside and outside a typical mammalian cell:
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