BLG 10A/B Lecture 1: Anatomy Week 1 chapter 17

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5 Nov 2016
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Centrifuge: denser elements at bottom, blood sample = hematocrit (blood fraction, males = 47% +/- 5, females 42% +/- 5% Platelets (help stop bleeding: leukocytes & platelets = <1, plasma makes up remaining 55% Albumin, globulins (antibodies), fibrogen: nutrients, electrolytes, gases, hormones. Red heme pigment bound to protein globin: four polypeptide chains. Two alpha; two beta: atom of iron in the centre. Carbon dioxide loading occurs in the tissues: forms carbaminohemoglobin, co2 binds with the amino acids instead of the heme group, occurs more readily in the reduced state (deoxygenated) Fetus has more hemoglobin has less oxygen availability in blood. Types of leukocytes: granulocytes, neutrophilis, eosinophilis, basophilis, agranulocytes (lack granules, lymphocytes, monocytes. Stabilizes the clot after 30 60 minutes fibrin strands. Platelets contract their myosin and actin proteins and pull on surrounding. Serum is squeezed (plasma without clotting proteins) from the mass. Compacts the clot, brings the edges of the blood vessel closer.

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