BCH 261 Lecture Notes - Lecture 2: Hydrogen Bond, Enzyme Catalysis, Amine

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All proteins are hetorpolymers made up of 20 amino acids. *name, 3 letter code, and 1 letter code. The carboxyl and amino group can act as an acid or base this is known as amphoteric. At 7. 2 ph the carboxyl donates an h (so it is deprotonated) and the amino group accepts the h (so it is protonated). The amino acids are overall neutral, except for the r group, such ions are called zwitterions. At the ph amino acids are dipolar ions = zwitterions. If high ph, h is released, and the molecule becomes negatively charged. If low ph , h is acquired and molecule becomes positively charged. (cationic form) Therefore all amino acids have l- and d- enantiomers. In vitro: synthesis of amino acids: 1:1 ratio of l and d. In the cells: amino acids are predominantly of the l- enantiomer. At a ph of 2. 19: 50% will be in form 1 and 50% in form 2.

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