PSYC 370 Lecture Notes - Lecture 9: Basal Ganglia, Genetic Testing, Cerebral Cortex

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Name: come from a physician who was the first person to describe the disease! The onset is most common between 35-45 that said some people don"t start showing symptoms till 60. If people start showing symptoms typically within 15-20 years of appearance of the disease that is when u see them dying. Here, it is more typical to see parkinsonian kind symptoms like muscle rigidity and the bradykini. Because it is a dominant disorder for any individual with a huntington parent- 50% risk of having the mutated gene themselves. The normal huntington gene only contains a few cag sequences. In health indi, 18-24 times of the cag repeats. In hunting, several of cag repeats -- -anything more than 39 repeats anywhere from 40 . Because you got a triplet of nucleotides, it is called a triploid repeat disorder. This is not the only triploid disorder out there- --

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