PSYC 271 Lecture Notes - Lecture 7: Cytoarchitecture, Cytoskeleton, Microglia

• School: Queen's University
• Department: Psychology
• Course: PSYC 271
• Professor: Peter Gagolewicz

Document Summary

To look at brain cells, you need to look at thing that are very small. Solution: microscopes; diff types including (1) light (2) o o. Light can go from 1-1500x normal combines multiple lenses to enlarge image; wavelength of light; good enough to study (1) cytoarchitecture of areas (3) look for damage neurons. Electron uses beams of light to create image; 1,000,000x; expensive & high e needs; cannot tissue; two types (1) transmission (2) scanning electron magnification; limited by stains (2) (4) shape of can magnify up to be used on live. Transmission (tem) shoots beam of electrons through a thin layer of tissue; must be thing enough for e- to pass through; allows study of parts of (1) cells (2) organelles (3) synapses (4) viruses. Scanning (sem) constructs 3-d pic of object; 250-500,000x magnification; biological samples must be dyed, fixed, & coated w/ high-contrast molecule (often gold); can visualized whole (1) neurons (2) parts of cells; cannot view interior.