MICR 360 Lecture Notes - Lecture 34: Tumor Suppressor Gene, Cervical Cancer, Rna Virus

• School: Queen's University
• Department: Microbiology and Immunology
• Course: MICR 360
• Professor: Sameh Basta

Document Summary

Normally our cells are programmed to grow, stop growing, and die to be replaced by other cells. Sometimes, our cells due to mutations and abnormal behaviour lose control of cell cycle, and at that point undergo neoplasm = abnormal growth cycle. Mutation causes failure and uncontrolled cell growth. Imp for programmed cell death, if mutation then abnormal cell death. Other infections include htlv-1, rna virus that infects t cells and cause leukemia. Hhv causes herpes, hide in latent phases and stays with you forever: kaposi"s sar(cid:272)o(cid:373)a hides i(cid:374) hiv positi(cid:448)e ppl. Hbv and hcv infects liver cells and can cause liver failure. Ebv infects b cells and limits their ability to expand and prod abs, and can make them cancer cells. In cases of hiv, start having other viruses show up as well. Cancer cells able to express specific type of antigens that immune may recognize.