MICR 121 Lecture Notes - Lecture 21: Ixodes Scapularis, Aedes Albopictus, Direct Fluorescent Antibody
14 Apr 2018
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Micr120 lecture 21: emerging infectious disease: zika, lyme, ebola. Current outbreak in south america no signs of slowing down: reproductive ratio of virus: # of secondary cases a viral infection generates in a fully susceptible population w no pre-existing immunity. Transmission: ro = 1 = unsustaina(cid:271)le out(cid:271)reak. Sexual contact: only arbovirus vector (majority of zika virus) Zika virus rna found in blood, semen, urine, vaginal fluid and saliva (found in semen as late as 50 days post illness onset) Zika virus in fetal brain at high concentrations. Pcr molecular assay in blood and urine (virus in urine >7days after detected in serum) flaviviruses are impeding dx. Caused by: spiral bacteria borrelia burdoferi sensu stricto. Life cycle of ixodes tick: 2 yr, 4 life stages (egg, larvae, nymph, adult), must have blood meal at qstage; after each meal it drops off from host and continues to next stage.
