BIOL 205 Lecture Notes - Lecture 8: Okazaki Fragments, Tata Box, Histone H2A
1 Dec 2014
School
Department
Course
Professor
Document Summary
10 base pairs per complete twist planar structures with vanderwaals forces. At have 2 h bonds stacking interactions btwn base pairs, interior of dna is hydrophobic, exterior hydrophilic structure double bonded structure stabilized by major and minor are important because they are grooves that proteins can recognize. Base stacking hydrophobic interactions cations (mg2+) minor groove is bound by tata box, because it has to be able to bend dna and unwind. Dna synthesis adding nucleotides one at a time to. 3" hydroxyl end requires a primer pyrophosphate is released, can be used to tell exactly when a nucleotide has been put in place. Dna polymerase 1 removes rna(exonuclease activity) , polymerase iii elongates on both strands okazaki fragments are pieces of rna fused to newly synthesized dna. Xes spot where replication starts clamp loader places clamp on. Dna dna poly 1 18-20 nucleotides but then it falls o .
